A Visual Approach to Explainable Computerized Clinical Decision Support

Abstract

Clinical Decision Support Systems (CDSS) provide assistance to physicians in clinical decision-making. Based on patient-specific evidence items triggering the inferencing process, such as examination findings, and expert-modeled or machine-learned clinical knowledge, these systems provide recommendations in finding the right diagnosis or the optimal therapy. The acceptance of, and the trust in, a CDSS are highly dependent on the transparency of the recommendation’s generation. Physicians must know both the key influences leading to a specific recommendation and the contradictory facts. They must also be aware of the certainty of a recommendation and its potential alternatives. We present a glyph-based, interactive multiple views approach to explainable computerized clinical decision support. Four linked views (1) provide a visual summary of all evidence items and their relevance for the computation result, (2) present linked textual information, such as clinical guidelines or therapy details, (3) show the certainty of the computation result, which includes the recommendation and a set of clinical scores, stagings etc., and (4) facilitate a guided investigation of the reasoning behind the recommendation generation as well as convey the effect of updated evidence items. We demonstrate our approach for a CDSS based on a causal Bayesian network representing the therapy of laryngeal cancer. The approach has been developed in close collaboration with physicians, and was assessed by six expert otolaryngologists as being tailored to physicians’ needs in understanding a CDSS.

Citation

Juliane Müller, Matthaeus Stoehr, Alexander Oeser, Jan Gaebel, Marc Streit, Andreas Dietz, Steffen Oeltze-Jafra
A Visual Approach to Explainable Computerized Clinical Decision Support
Computer & Graphics, Special Section on VCBM 2019, 91: 1-11, doi:10.1016/j.cag.2020.06.004, 2020.

BibTeX

@article{2020_cg_clinical-decision-support,
    title = {A Visual Approach to Explainable Computerized Clinical Decision Support},
    author = {Juliane Müller and Matthaeus Stoehr and Alexander Oeser and Jan Gaebel and Marc Streit and Andreas Dietz and Steffen Oeltze-Jafra},
    journal = {Computer & Graphics, Special Section on VCBM 2019},
    doi = {10.1016/j.cag.2020.06.004},
    volume = {91},
    pages = {1-11},
    year = {2020}
}

Acknowledgements

The research leading to this work was supported by the German Federal Ministry of Education and Research (BMBF) (03Z1LN11) and the Federal State of Saxony-Anhalt (FKZ: I 88).