TourGuide: Navigation system for recording and analysis of complex clinical data for personalized medicine

Life science researcher are facing a growing amount of research data. This is a challenge regarding the structure acquisition and storage, but also the analysis. Without adequate tools for data acquisition, handling and analysis the search for new patterns and correlations is proverbially a search for a needle in a haystack. This project aims to combine successful means of data visualization with a generic research platform for medical research. A integrative research platform will be created which covers the whole process of knowledge discovery from data modeling, over acquisition and handling to analysis.

In this project we aim to create an integrated research (data) infrastructure that actively guides the medical expert through this process and provides support in tasks that usually require profound IT knowledge. This guidance is a fundamental aspect of the system and is not only responsible for showing the user in which part of the knowledge discovery process she is currently working, but also for giving hints and revealing possible consequences of currently available options. For each part of the process different algorithms and methods are necessary to provide this guidance. In the phase of data modeling, e.g., it is necessary to analyze the data model, while in the phase of data exploration statistical and machine learning algorithms are used to grab the attention of the user to discovered correlations, patterns and outliers.

Journal Publications

Christina Stoiber, Florian Grassinger, Margit Pohl, Holger Stitz, Marc Streit, Wolfgang Aigner
Visualization Ahoi! Getting the User Aboard
IEEE Conference on Information Visualization (InfoVis, under review), 2019.
Davide Ceneda, Natalia Andrienko, Gennady Andrienko, Theresia Gschwandtner, Silvia Miksch, Tobias Schreck, Marc Streit, Josef Suschnigg, Christian Tominski
Guide Me in Analysis: A Framework for Guidance Designer
IEEE Conference on Visual Analytics Science and Technology (VAST, under review), 2019
Klaus Eckelt, Patrick Adelberger, Thomas Zichner, Andreas Wernitznig, Marc Streit
TourDino: A Support View for Confirming Patterns in Tabular Data
EuroVis Workshop on Visual Analytics (EuroVA '19), to appear
Paper Homepage
Marc Streit, Samuel Gratzl, Holger Stitz, Andreas Wernitznig, Thomas Zichner, Christian Haslinger
Ordino: a visual cancer analysis tool for ranking and exploring genes, cell lines and tissue samples
Bioinformatics, 2019
Paper Homepage
Katarina Furmanova, Samuel Gratzl, Holger Stitz, Thomas Zichner, Miroslava Jaresova, Martin Ennemoser, Alexander Lex, Marc Streit
Taggle: Scalable Visualization of Tabular Data through Aggregation
arXiv preprint (under review), 2019
arXiv
Holger Stitz, Samuel Gratzl, Harald Piringer, Thomas Zichner, Marc Streit
KnowledgePearls: Provenance-Based Visualization Retrieval
EEE Transactions on Visualization and Computer Graphics (VAST '18), 25(1): 120--130, 2018
Paper Homepage
Christina Niederer, Holger Stitz, Reem Hourieh, Florian Grassinger, Wolfgang Aigner, Marc Streit
TACO: Visualizing Changes in Tables Over Time
IEEE Transactions on Visualization and Computer Graphics (InfoVis '17), 24(1), pp. 677-686, 2017.
Marc Streit, Dominic Girardi, David Fuchs
Bericht über TourGuide Projekt
JKU & Partners, Whitebook Medical Technology Upper Austria, ISBN 987-3-200-05215-4, pp. 82-83, 2017.
Davide Ceneda, Theresia Gschwandtner, Thorsten May, Silvia Miksch, Hans-Jörg Schulz, Marc Streit, Christian Tominski
Characterizing Guidance in Visual Analytics
IEEE Transactions on Visualization and Computer Graphics (VAST '16), 23(1), pp. 111-120, 2017
PDF | Publisher
Samuel Gratzl, Alexander Lex, Nils Gehlenborg, Nicola Cosgrove, Marc Streit
From Visual Exploration to Storytelling and Back Again
Computer Graphics Forum (EuroVis '16), vol. 35, no. 3, pp. 491-500, 2016
Paper Homepage

Extended Abstracts and Posters

David Fuchs, Sebastian Graf, Thomas Gitter, Steffen Krause, Klaus Eckelt, Sandra Wartner, Holger Stitz, Dominic Girardi, Marc Streit, Clemens A. Schmitt
Reasons For Failure To Give Adjuvant Chemotherapy In Early Breast Cancer - Interactive Visual Analysis Of Clinical Data With The TourGuide Software
OeGHO & AHOP Spring Conference 2019, Linz, Austria, 2019
Poster Abstract | Poster
Klaus Eckelt, Sandra Wartner, Holger Stitz, David Fuchs, Thomas Gitter, Dominic Girardi, Sebastian Graf, Steffen Krause, Clemens A. Schmitt, Marc Streit
TourGuide: Interactive Visual Analysis of Clinical Oncology Data
OeGHO & AHOP Spring Conference 2019, Linz, Austria, 2019
Poster Abstract | Poster
Ontologie-gestützte Visualisierung zur explorativen medizinischen Datenanalyse
Kepler Science Day, 22.11.2017
Katarina Furmanova, Miroslava Jaresova, Bikram Kawan, Holger Stitz, Martin Ennemoser, Samuel Gratzl, Alexander Lex, Marc Streit
Taggle: Scaling Table Visualization through Aggregation
IEEE Conference on Information Visualization (InfoVis ’17), Phoenix, AZ, USA, 2017
Poster Abstract | Poster | Video
Holger Stitz, Samuel Gratzl, Harald Piringer, and Marc Streit
Provenance-Based Visualization Retrieval
IEEE Conference on Visual Analytics Science and Technology (VAST ’17), Phoenix, AZ, USA, 2017
IEEE VAST 2017 Best Poster Award Poster Abstract | Poster | Video
Reem Hourieh, Holger Stitz, Nils Gehlenborg, Marc Streit
TaCo: Comparative Visualization of Large Tabular Data
Poster Compendium of the Eurographics/IEEE Symposium on Visualization (EuroVis ’16), Groningen, Netherlands, 2016.
Poster Abstract | Poster | Video

Talks

11.11.2015
Kepler Science Day
Vortragender: Prof. Marc Streit
29.02.2016
Gründungskommission der Medizin-Fakultät an der Johannes Kepler Universität
Vortragender: Prof. Marc Streit
13.10.2016
Veranstaltung DIGITAL MEDTECH – be inspired!, Medizintechnik-Cluster, Business Upper Austria, OÖ Wirtschaftsagentur GmbH
Vortragender: Dr. David Fuchs und Prof. Marc Streit
23.02.2017
Daten sehen - Krebs verstehen. Mit Big Data-Analyse und Visualisierung dem Krebs auf der Spur, JKU Next Generation Vortragsreihe im Ars Electronica Center Linz, Linz, Austria.
Vortragender: Prof. Marc Streit
27.02.2017
From Visual Exploration to Storytelling and Back Again, Visual Computing Center, King Abdullah University of Science & Technology (KAUST) (invited talk), Thuwal, Saudi Arabia.
Vortragender: Prof. Marc Streit
20.04.2017
From Visual Exploration of Biomedical Data to Storytelling and Back Again, 3rd BiVi (Biological Visualisation Community) Annual Meeting (keynote address), Edinburgh, UK.
Vortragender: Prof. Marc Streit
09.05.2017
AEC GET-INSPIRED Veranstaltung im Ars Electronic Center Linz.
Vortragender: Prof. Marc Streit
23.08.2017
Visualization for Decision Making: Going (Far) Beyond Static Plots, GSK Visualisation Day (keynote address) Stevenage, UK.
Vortragender: Prof. Marc Streit
01.10.2017
Taggle Poster Präsentation auf IEEE VIS Konferenz in Phoenix, USA.
Vortragender: Martin Ennemoser
01.10.2017
Provenance-Based Retrieval Poster Präsentation auf der IEEE VIS Konferenz in Phoenix, USA.
Vortragender: Holger Stitz
27.11.2017
Leveraging Provenance for Storytelling, Reproducibility, and Recall, Vienna, Austria., VRVis Forum (invited talk)
Vortragender: Prof. Marc Streit
23.01.2018
Collaborating with Domain Experts, Dagstuhl Seminar on Foundations of Data Visualization (invited talk), Dagstuhl, Germany.
Vortragender: Prof. Marc Streit
06.03.2018
Interactive Exploration of Structured Data, Large (Biomedical) Graphs, and Black Box Models, Visual AI Lab, IBM Research (invited talk), Cambridge, MA, USA.
Vortragender: Prof. Marc Streit
07.03.2018
Injecting Life into Visualizations for Biomedical Research, Open Insights Seminar Series, Harvard Medical School (invited talk), Cambridge, MA, USA.
Vortragender: Prof. Marc Streit
14.03.2018
Leveraging Provenance for Storytelling, Reproducibility, and Recall, University of Groningen (invited talk), Groningen, Netherlands.
Vortragender: Prof. Marc Streit
16.03.2018
Leveraging Provenance for Storytelling, Reproducibility, and Recall, GRIS Kolloquium, TU Darmstadt (invited talk), Darmstadt, Germany.
Vortragender: Prof. Marc Streit
16.04.2018
Collaborations between VIS / Bioinformatics / BIO Communities, Dagstuhl Seminar on Visualization of Biological Data - Crossroads (invited talk), Dagstuhl, Germany.
Vortragender: Prof. Marc Streit
03.06.2018
Human-Interpretable AI, Collaboration Kick-off JKU Linz and Imperial College London (invited talk), London, UK.
Vortragender: Prof. Marc Streit
13.06.2018
Multi-Dimensional Data Vis in Drug Discovery: From Target Identification to Validation, EMBL EBI Industry Programme Workshop: Innovations in Data Visualisation for Drug Discovery (invited talk), Cambridge, UK.
Vortragender: Prof. Marc Streit
12.07.2018
Leveraging Provenance for Storytelling, Reproducibility, and Recall, SCI Seminar, University of Utah (invited talk), Salt Lake City, UT, USA.
Vortragender: Prof. Marc Streit
08.01.2019
Visual Data Science: Daten sehen, Daten verstehen, Antrittsvorlesung Professur an der JKU Linz, Linz, Austria.
Vortragender: Prof. Marc Streit
03.06.2019
Trust Me, I am a Visualization, Invited Keynote EuroVis Workshop on Trustworthy Visualization (TrustVis), Porto, Portugal.
Vortragender: Prof. Marc Streit

Theses

Holger Stitz | PhD Thesis
Interactive Focus+Context Analysis of Time-Series and Provenance Data
Supervision: Prof. Marc Streit
Thesis
Klaus Eckelt | Diploma Thesis
Data-Driven User Guidance in Multi-Attribute Data Exploration
Supervision: Ao.Prof. Eduard Gröller & Prof. Marc Streit
Thesis
Samuel Gratzl | PhD Thesis
Visually Guiding Users in Selection, Exploration, and Presentation Tasks Supervision: Prof. Marc Streit
Reem Hourieh | Master's Thesis
Comparative Visualization of Large Tabular Data
Supervision: Prof. Marc Streit